The Northeastern Pennsylvania Alliance is a nonprofit, regional community and economic development agency with a 50-member board of directors.

The alliance was organized in 1964 by the private sector as a nonprofit community and economic development agency. NEPA became a Local Development District and an Economic Development District by federal law in 1965.It was then designated as an Local Development District by state law in 1994.It recognized the value of a regional approach to economic development.It is now a federal, state and local partnership, with representation from the public and the private sectors, with 51 percent public sector representation.It has a regional population of 1,021,027 as of July 1, 2013.It provides regional coverage of 4,476 square miles.