Pope Francis has signed off on the miracle needed to make Mother Teresa a saint, giving the tiny nun who cared for the poor one of the Catholic Church’s highest honors just two decades after her death.

The Vatican announced Francis approved a decree attributing a miracle to Mother Teresa’s intercession during an audience with the head of the Vatican’s saint-making office.

The miracle responsible for Mother Teresa’s canonization concerned an inexplicable cure of a Brazilian man suffering from a viral brain infection that resulted in multiple abscesses. By Dec. 5, 2006, he was in a coma and dying, suffering from an accumulation of fluid around the brain. Prior to a scheduled surgery, he sat up, awakened without pain and a day later was declared symptom-free, which was attributed to Mother Teresa’s intercession.