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TTP Symptoms

Published June 03. 2011 05:15PM

Blood clots, a low platelet count, and damaged red blood cells cause the signs and symptoms of thrombotic thrombocytopenic purpura (TTP).

The signs and symptoms include:

• Purplish bruises on the skin or mucous membranes (such as on the mouth) due to bleeding under the skin. These bruises are called purpura.

• Pinpoint-sized red or purple dots on the skin that often are found in groups and may look like a rash. The spots, called petechiae, are due to bleeding under the skin.

• Paleness or jaundice (a yellowish color of the skin or whites of the eyes).

• Fatigue (feeling very tired and weak).

• Fever.

• A fast heart rate or shortness of breath.

• Headache, speech changes, confusion, coma, stroke, or seizure.

• A low amount of urine, or protein or blood in the urine.

Source: National Institutes of Health

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